Table 3

Results of univariate and multivariate analyses: factors potentially associated with survival time (P<0.05) in dogs with newly diagnosed diabetes mellitus

VariableMedian survival time, days (P value, log-rank test)Hazard ratio (95% confidence interval)P value, Cox regression
Univariate Cox regression analysis
 Age1.01 (1.00 to 1.02)0.042
 Breed (purebred v crossbred)1089 v 916 (0.025)2.17 (1.08 to 4.37)0.028
 Red blood cell count1.00 (1.00 to 1.00)0.007
 Haematocrit value1.08 (1.02 to 1.15)0.008
 Glucose1.04 (1.01 to 1.07)0.008
 Alkaline phosphatase1.00 (1.00 to 1.00)0.012
 Urea1.01 (1.00 to 1.02)0.008
 Creatinine1.00 (1.00 to 1.00)0.012
 Phosphate1.81 (1.11 to 2.94)0.015
 Sodium0.94 (0.90 to 0.99)0.037
 Concurrent diseases (0=absence v 1=presence)*1089 v 781 (0.045)1.94 (1.00 to 3.78)0.049
 Cushing’s syndrome (0=absence v 1=presence)993 v 645 (0.038)2.46 (1.01 to 5.97)0.045
Multivariate Cox regression analysis
 Haematocrit value1.06 (1.00 to 1.13)0.032
 Phosphate1.83 (1.13 to 2.97)0.013
  • Survival time of diagnostic groups was estimated by Kaplan-Meier analysis and compared by log-rank test.

  • *Concurrent diseases also include Cushing’s syndrome.