Table 5

Data extracted from studies using the method of Haywood et al 10 for caffeine

StudynDaily dose
(mg/horse)
Application schemeCmax plasma
(ng/ml)
Cmax urine
(ng/ml)
Dyke and Sams52 37.3Once a day for eight days50
Bonnaire et al 36 210Once a day for two days50
Respondek et al 35 552.5 mg twice a day for three days30
5157.5 mg twice a day for three days70
Ohtake et al 25 412.5Once2752
425Once65131
  • cmax, maximum concentration; n, number of horses.