Data extracted from studies using the method of Haywood et al 10 for caffeine
| Study | n | Daily dose (mg/horse) | Application scheme | Cmax plasma (ng/ml) | Cmax urine (ng/ml) |
| Dyke and Sams52 | 3 | 7.3 | Once a day for eight days | – | 50 |
| Bonnaire et al 36 | 2 | 10 | Once a day for two days | – | 50 |
| Respondek et al 35 | 5 | 5 | 2.5 mg twice a day for three days | – | 30 |
| 5 | 15 | 7.5 mg twice a day for three days | – | 70 | |
| Ohtake et al 25 | 4 | 12.5 | Once | 27 | 52 |
| 4 | 25 | Once | 65 | 131 |
cmax, maximum concentration; n, number of horses.