Table 4

Amino acid changes (presence of stop codons and changes in hydrophobicity) identified in the seven veterinary Pseudomonas aeruginosa isolates by whole genome sequencing

Function Gene85688690399498210901098
Cell metabolism-associated pyrC G423STOPG423STOP
pdxB V109KD324AV109K
aroB A200EA200EA200EA200EA200EA200EA200E
Acquired/adaptive resistance through LPS modification parR L153RL153RL153RL153RL153R
parS A115E
Recycling of cell wall components mpl A404P
E451STOP
Transcriptional regulator-associated with resistance to antibiotics ampR E114A
M228R
R291STOP
E114A
E172V
E114A
M228R
E114A
M228R
Activation of LPS-modifying operon by mutations in TCSs pmrA L71RL71RL71RL71RL71R
LPS biosynthesis-related functions wapR W114R
295STOP
Modification of lipid A or Kdo with aminoarabinose arnC P23A
arnD A284D
arnF P137L