Table 1

Demographic data and measurements of the hippocampal formation in the young (1–3 years old) and the old (>10 years of age) groups

Young group (n=75)Old group  n=44)P value
Age
(months)
22±9142±18<0.0001
Body weight
(kg)
20.5±12.521±11.20.81
Sex14F, 16FS, 18M, 27MN0F, 22FS, 3M , 19MN0.34
Observer 1Observer 2Observer 1Observer 2
Left HFH
(mm)
8.26±0.818.26±0.827.33±0.887.32±0.89<0.0001*
Right HFH
(mm)
8.25±0.878.25±0.877.43±0.867.43±0.86<0.0001*
mHFH
(mm)
8.26±0.818.26±0.817.38±0.847.38±0.84<0.0001*
HB
(mm)
45.66±3.5345.65±3.5547.26±3.9647.27±3.980.024*
mHFH/HB ratio
(%)
18.30±1.6218.10±1.6215.66±1.6615.65±1.66<0.0001*
  • *P value indicates statistically significant differences between young and old groups and not within each group.

  • Observer 1=AG, resident in neurology. Observer 2=OT, board-certified veterinary radiologist.

  • HB, height of the brain; HFH/HB ratio, hippocampal formation to brain ratio; HFH, hippocampal formation height; mHFH, mean hippocampal formation height