TABLE 2:

Frequencies of QK222 PRNP genotypes in goat breeds and other PRNP gene variation by breed

BreedAlpineAnglo- NubianAngoraBoerCashmereGolden-GuernseyPygmySaanenToggenburgSaanenX, ToggenburgXOthers*All
Herds n1115514142241710552
Goats n51120140254294029211183140391236
QK222 n (%)02 (1.7)000004 (1.9)1 (0.5)1 (0.7)08 (0.6)
Other detected polymorphisms
R101R101
G102G102
S127S127S127S127S127S127
M142M142M142M142M142M142M142
R143R143R143R143R143
S146S146
H154H154
Q211Q211Q211Q211Q211Q211
L218L218
P240S†P240SP240SP240SP240SP240SP240SP240SP240SP240SP240SP240S
  • *One herd represented by 30 animal samples could not be specifically classified as the information given by farmer was “Saanen, Toggenburg, Alpine, Anglo-Nubian”; six animals were described as ‘British goat’, one as ‘mix’ and two were Bagot

  • †The variation in codon 240 occurs in different combinations with the other polymorphisms and is also present in all breeds as a polymorphism of the wild-type allele: IRRQ-S240 or IRRQ-P240