Trial | n start (h) | n start (p) | n start (total) | n end (h) | n end (p) | n end (total) | Attrition (per cent) | Main outcome | Problem with main outcome? | Main outcome used for data extraction | Endpoint | Notes |
---|---|---|---|---|---|---|---|---|---|---|---|---|

Individualised homeopathy/treatment | ||||||||||||

A01 | 21 | 16 | 37 | 21 | 16 | 37 | 0.0 | Acute mastitis score | No (though sd calculated from 95 per cent CI data, using t-distribution) | Acute mastitis score | Seven days | |

A02 | 58 | 43 | 101 | 58 | 43 | 101 | 0.0 | Totally cured quarters | No | Totally cured quarters | Seven days | n=number of udder quarters |

Non-individualised homeopathy/treatment | ||||||||||||

A05 | 24 | 24 | 48 | 24 | 20 | 44 | 8.3 | Duration of diarrhoea | Yes: sds not given, but common sd calculated from CI data (assuming 95% CI) | Duration of diarrhoea | Up to eight days | |

A09 | 6 | 10 | 16 | 6 | 9 | 15 | 6.3 | Animals with 'pasty' stools | No | Animals with 'pasty' stools | 48 hours | Authors did not carry out formal statistical analysis of data |

A04 | 35 | 40 | 75 | 34 | 38 | 72 | 4.0 | Improved (that is reduced) fear response | No | Improved (that is reduced) fear response | Four weeks | |

A11 | 18 | 23 | 41 | 18 | 23 | 41 | 0.0 | Presence of uterine contraction | No | Presence of uterine contraction | 20 minutes after treatment | Contractions after birth of first piglet. n=1 excluded from homeopathy group (repeat measurement of placebo group animal) |

A06 | 76 | 70 | 146 | 58 | 56 | 114 | 21.9 | Gestating cows | No | Gestating cows | 200 days post-partum | |

A28 | 60 | 30 | 90 | 50 | 26 | 76 | 15.6 | Held to first service | No (original percentage data used for calculation of odds ratios) | Held to first service | Not stated | n for homeopathy is total for two homeopathically treated groups. It was assumed that a total of 120 cows were randomised to four equal groups |

A03 | Data not given | Data not given | 416 | Data not given | Data not given | 306 | 26.4 | Bacterial cell counts | Yes, data not given | None usable | 37 days | n reflects number of quarters, not number of animals |

A08 | 76 | 76 | 152 | 68 | 67 | 135 | 11.2 | Somatic cell counts (only outcome recorded) | Yes, sd not available (logarithmic data) | None usable | 28 days | |

A10 | 52 | 52 | 104 | 51 | 52 | 103 | 1.0 | Unaffected quarters | No | Unaffected quarters | 30 days | n=number of udder quarters. Unaffected quarters identified by CMT |

A07 | 17 | 17 | 34 | 14 | 15 | 29 | 14.7 | Improved mobility index | No | Improved mobility index | Eight weeks | Assumes that total n=51 was divided equally into three groups |

Non-individualised homeopathy/prophylaxis | ||||||||||||

A23 | 417 | 200 | 617 | 417 | 200 | 617 | 0.0 | Absence of endometritis | No | Absence of endometritis | 21 to 27 days | |

A24 | 26 | 26 | 52 | 24 | 26 | 50 | 3.8 | Absence of diarrhoea | No | Absence of diarrhoea per litter | One week | The sows were treated. n=number of litters |

A26 | 39 | 40 | 79 | 39 | 40 | 79 | 0.0 | Piglets' final bodyweight | Yes: sd not given, but common sd calculated from conservative P=0.049 | Piglets' final bodyweight | 30 days | |

A22 | 480 | 480 | 960 | 480 | 480 | 960 | 0.0 | Absence of respiratory tract disease | No | Absence of respiratory tract disease | 11 days | |

A25 | Not stated | Not stated | 19 | Not stated | Not stated | 19 | 0.0 | Plasma glucose | Yes, data not given | None usable | Three weeks after parturition | Assumes that half of the 38 randomised animals received homeopathy or placebo. 'Main outcome' decided on coin toss |

A27 | 94 | 31 | 125 | 94 | 31 | 125 | 0.0 | Parturition | No | Parturition | Not stated | Sperm was treated |

CI Confidence interval, CMT California mastitis test, h Homeopathy group(s), n Number, p Placebo group(s), sd Standard deviation