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Porcine circovirus type 3 detection in a Hungarian pig farm experiencing reproductive failures
  1. Zoltán Deim1,
  2. László Dencső2,
  3. Ildikó Erdélyi3,
  4. Sarshad Koderi Valappil2,
  5. Csaba Varga4,
  6. Anikó Pósa5,
  7. László Makrai6 and
  8. Gábor Rákhely2
  1. 1 Interdisciplinary Excellence Centre, Department of Biotechnology, Szegedi Tudomanyegyetem, Szeged, Hungary
  2. 2 Department of Biotechnology, Szegedi Tudomanyegyetem, Szeged, Hungary
  3. 3 Pathology, Allatorvostudomanyi Egyetem, Budapest, Hungary
  4. 4 Department of Physiology, Anatomy and Neuroscience, Szegedi Tudomanyegyetem, Szeged, Hungary
  5. 5 Interdisciplinary Excellence Centre, Department of Physiology, Anatomy and Neuroscience, Szegedi Tudomanyegyetem, Szeged, Hungary
  6. 6 Department of Microbiology and Infectious Diseases, Allatorvostudomanyi Egyetem, Budapest, Hungary
  1. E-mail for correspondence; deim.igszak{at}gmail.com

Abstract

Porcine circovirus 3 (PCV3) infection has been reported in piglets and sows with porcine dermatitis and nephropathy syndrome, reproductive failure, and cardiac and multisystemic inflammation. Few studies linked PCV3 infection to increased incidence of abortion and weak-born piglets. This is the first report of a detection of PCV3 Hungarian strain in several organs of aborted and weak-born piglets, including the thymus, lymph node, placenta, spleen, kidney and the liver. The tissue tropism of PCV3 in affected litters was analysed using real-time quantitative PCR, and the result showed the highest load of viral DNA in the thymus and lymph nodes. The ORF2 of Hungarian PCV3 strains was 524 nucleotides in length, and the sequence identity to GenBank sequences ranged from 98.5 per cent to 99.2 per cent. The results suggest that PCV3 may have a relevant role in reproductive failure in gilts.

  • porcine circovirus type 3
  • reproductive failure
  • weak-born
  • Pcv3
  • hungary

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Footnotes

  • Funding This work was supported by the European Union (grant number: EFOP -3.6.1 -16 -2016 -00008). The Ministry of Human Capacities, Hungary (grant 20391-3/2018/FEKUSTRAT) is acknowledged (AP and ZD). This work was co-worked by GINOP-2.1.5-15-2016-00007 .

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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