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Equine medicine
Genetics of equine metabolic syndrome
  1. Carolina E. Rodríguez-Sanz,
  2. Natalia Sevane and
  3. Susana Dunner
  1. Department of Animal Production, Veterinary Faculty, Complutense University of Madrid, Madrid 28040, Spain
  1. email: caroro07{at}

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Equine metabolic syndrome (EMS) is defined as a complex disorder characterised by a phenotype of insulin dysregulation, obesity and a predisposition toward laminitis, resulting from the combination of one or more inherited genetic alleles and environmental influences.1

Recently, a genome-wide association study (GWAS)2 identified two genetic markers for EMS located in the FAM174A gene region in Arabian horses: BIEC2-263524-C and FAM174A 3’ UTR -11(G) (Equus caballus chromosome 14:69,276,814 and 14:69,119,991 …

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