Statistics from Altmetric.com
It is very common for the veterinary practitioner to be presented with canine patients suffering from polyuria and polydipsia (PUPD); that is, increased urine output and water intake, respectively. But determining a diagnostic approach can be very difficult as there are many causes.
PUPD can be due to either primary polydipsia with secondary polyuria or primary polyuria with compensatory polydipsia. Primary polyuria is when decreased urine concentrating ability – due to a lack of antidiuretic hormone (ADH), renal insensitivity to ADH, or an osmotic diuresis – leads to compensatory polydipsia. Most water balance disorders fall into this category. Primary polydipsia is when increased thirst leads to compensatory polyuria to excrete the excess water. Primary polydipsia is uncommon, and is normally due to behavioural disorders (ie, psychogenic polydipsia) or defects in the thirst centre.
Fig 1 shows a diagnostic algorithm that we have designed for investigating PUPD in dogs.
Detailed history taking provides essential clues to guide investigation of PUPD. Ideally, water intake should be accurately quantified before embarking on further investigations to avoid unnecessary and potentially expensive diagnostics. It is also imperative to distinguish between …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.