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Infection dynamics of porcine circovirus type 3 in longitudinally sampled pigs from four Spanish farms
  1. Francini Klaumann1,2,
  2. Florencia Correa-Fiz2,
  3. Marina Sibila2,
  4. José Ignacio Núñez2 and
  5. Joaquim Segalés3,4
  1. 1 CAPES Foundation, Ministry of Education of Brazil, Brazilia, DF, Brazil
  2. 2 IRTA, Centre de Recerca en Sanitat Animal (CReSA), IRTA-UAB, Bellaterra, Barcelona, Spain
  3. 3 UAB, Centre de Recerca en Sanitat Animal (CReSA), IRTA-UAB, Bellaterra, Barcelona, Spain
  4. 4 Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, Bellaterra, Barcelona, Spain
  1. E-mail for correspondence; joaquim.segales{at}


Porcine circovirus type 3 (PCV-3) is a recently discovered virus in domestic pigs and wild boar. The virus has been described in pigs with different clinical/pathological presentations and healthy animals, but the dynamics of infection is currently unknown. The aim of this study was to longitudinally monitor PCV-3 infection in 152 pigs from four different healthy farms (A, B, C and D) by means of PCR in serum. The selected animals were sampled five (farm A) or six (farms B–D) times from weaning until the end of the fattening period. PCV-3 genome was found in pigs from all tested ages and farms; few animals had an apparent long-term infection (4–23 weeks). PCV-3 frequency of detection remained fairly uniform along tested ages within farms A and C, but was more variable among sampling times in farms B and D. Eight partial genome sequences were obtained from six different animals. Phylogenetic tree and pairwise distance analysis showed high similarity among sequences and with available genomes from different countries. This is the first study on PCV-3 infection dynamics in longitudinally sampled pigs. Most pigs got infection during their life, although PCV-3 did not appear to be linked with any specific age.

  • infection dynamics
  • longitudinal
  • domestic pig
  • PCR
  • porcine circovirus 3
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  • Funding This study is funded by Instituto Nacional de Investigación y Tecnologia Agraria y Alimentaria (E-RTA2017-00007-00-00).

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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