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Serum cobalamin and folate are prognostic for canine exocrine pancreatic insufficiency

N. Soetarta, D. Rochela, A. Drut and others

The Veterinary Journal (2019) 243, 15–20

doi: 10.1016/j.tvjl.2018.11.003

• What did the research find?

A strong breed disposition for canine exocrine pancreatic insufficiency (EPI) was observed, with German shepherd dogs accounting for nearly 48 per cent of the cases included in this study. The prognosis for EPI was found to be poorer in male dogs, older dogs, dogs with dysorexia and/or hypocobalaminaemia at diagnosis and dogs that did not receive enzyme supplementation therapy. Conversely, the prognosis was improved for dogs with high serum folate concentration at diagnosis.

• How was it conducted?

The medical records of 299 dogs with an initial diagnosis of EPI were retrospectively reviewed. The data extracted included breed, age, weight, serum cobalamin and folate results and details of the initial treatment provided. Follow-up was carried out to collect outcome information, using a survey sent …

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