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Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK
  1. Kim B Stevens1,8,
  2. Dan O’Neill1,
  3. Rosanne Jepson2,
  4. Laura Phillipa Holm3,
  5. David John Walker3 and
  6. Jacqueline Martina Cardwell1
  1. 1 Department of Pathobiology and Population Sciences, Royal Veterinary College, Hatfield, UK
  2. 2 Department of Clinical Science and Services, Royal Veterinary College, Hatfield, UK
  3. 3 Anderson Moores Veterinary Specialists, London, UK
  4. 8 Kimene Analytics Ltd, London, UK
  1. E-mail for correspondence; kstevens{at}rvc.ac.uk

Abstract

Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased or decreased risk of being diagnosed with CRGV, and to report on age and sex distributions of CRGV cases occurring in the UK. Multivariable logistic regression was used to compare 101 dogs diagnosed with CRGV between November 2012 and May 2017 with a denominator population of 446,453 dogs from the VetCompass database. Two Kennel Club breed groups—hounds (odds ratio (OR) 10.68) and gun dogs (OR 9.69)—had the highest risk of being diagnosed with CRGV compared with terriers, while toy dogs were absent from among CRGV cases. Females were more likely to be diagnosed with CRGV (OR 1.51) as were neutered dogs (OR 3.36). As well as helping veterinarians develop an index of suspicion for the disease, better understanding of the signalment risk factors may assist in the development of causal models for CRGV and help identify the aetiology of the disease.

  • epidemiology
  • kennel club breed-groups
  • signalment
  • risk factors
  • vetcompass
  • alabama rot
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Footnotes

  • Contributors KBS performed all analyses and wrote the first draft of the paper. LPH and DJW compiled the case data set. DON compiled the VetCompass dog denominator data set. All authors contributed substantially to the interpretation of data, drafting of the final manuscript and critical revision for important intellectual content. All authors approved the final version of the manuscript for submission.

  • Funding This study was generously funded by the New Forest Dog Owners Group (NFDog) and the Alabama Rot Research Fund (ARRF).

  • Competing interests None declared.

  • Ethics approval Ethics approval was granted by the RVC Ethics and Welfare Committee (reference number URN 2015 1369).

  • Provenance and peer review Not commissioned; externally peer reviewed.

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