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Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales
  1. Sylvia S Grierson1,
  2. Dirk Werling2,
  3. Cornelia Bidewell3 and
  4. Susanna Williamson3
  1. 1 Department of Virology, Animal and Plant Health Agency, Woodham Lane Addlestone, Surrey, UK
  2. 2 The Royal Veterinary College, Hawkshead Lane, North Mymms Hatfield, Hertfordshire, UK
  3. 3 Animal and Plant Health Agency, Rougham Hill Bury St Edmunds, Suffolk, UK
  1. E-mail for correspondence; sylvia.grierson{at}


Confirmed cases of porcine circovirus disease (PCVD) in Great Britain have shown a steady decline since the availability of porcine circovirus type 2 (PCV2) vaccines. However, PCVD is still occasionally diagnosed. The authors carried out a genotyping study to characterise PCV2 associated with confirmed PCVD cases in England and Wales from 2011 to January 2016 (n=65). A partial fragment of PCV2 genome encompassing ORF2 was amplified and sequenced from 45 cases of PCVD. The majority of sequences were genotype PCV2b but four sequences were PCV2d. The significance of the emergence of PCV2d in England and elsewhere in the world is not yet known, although it does appear to represent an ongoing global genotype shift.

  • Pigs
  • Virology
  • Porcine Circovirus
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  • Funding This work was funded by Defra within the APHA project ‘Scanning surveillance for pig diseases in England and Wales (ED1200)'.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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