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Dog breeding
Inherited pathology and pet trading
  1. Luis V. Monteagudo,
  2. M. Teresa Tejedor,
  3. Alicia Uixerá,
  4. Olga Mitjana,
  5. M. Victoria Falceto and
  6. Cristina Bonastre
  1. Faculty of Veterinary Sciences, University of Zaragoza, Miguel Servet 177, 50013-Zaragoza, Spain
  1. e-mail: monteagu{at}

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RECENTLY, two miniature schnauzer dogs affected by persistent Müllerian duct syndrome (PMDS) have been referred by independent local veterinary practitioners to the Faculty of Veterinary Sciences in Zaragoza, Spain. In light of the observed malformations in the genitalia, we performed DNA sequencing and verified that both dogs were homozygous carriers of the MISRII locus mutation, identified previously in the literature to be responsible for PMDS in this breed in the USA (Wu and others 2009). PMDS has been reported in miniature schnauzers in the Netherlands (Vegter and others 2010) and in Japan (Matsuu and others 2009), but in these cases the presence of this mutation was not …

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