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Antimicrobial resistance
Antimicrobial resistance and bacterial density
  1. R. W. Humphry and
  2. G. J. Gunn
  1. Epidemiology Research Unit, SRUC, Drummondhill, Stratherrick Road, Inverness IV2 4JZ
  1. e-mail: roger.humphry{at}

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‘ONE Health’ requires ‘one language’ (Ismail 2012), and this applies to antimicrobial resistance, where there is progress on standardising procedures (eg, European Committee on Antimicrobial Susceptibility Testing [EUCAST]). However, most methods measure resistance at the isolate-level and, often, only a single isolate per sample is tested. We suggest that measurements of both isolate-level prevalence and bacterial density are desirable (eg, for modelling transfer of resistance from livestock to humans).

Bacterial density matters, because densities vary by orders of magnitude, and the concentration of resistant bacteria (mg−1) is the product of …

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