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Multiple (disseminated) follicular cysts in five dogs and one cat
  1. A. White, DVM1,
  2. A. Stern, DVM, DipACVP3,
  3. K. Campbell, DVM, MS, DipACVD, DipACVIM1 and
  4. D. Santoro, DVM, MS, DrSC, PhD, DipACVD, DipECVD2
  1. 1Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA
  2. 2University of Florida, College of Veterinary Medicine, 2015 SW 16th Ave, Gainesville, FL 32608, USA
  3. 3Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA
  1. E-mail for correspondence: dsantoro{at}

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Cutaneous cysts are common non-neoplastic, non-inflammatory tumor-like lesions defined as epithelial-lined sac-like structures filled with keratin, hair and sebum (Scott and others 2001). Follicular cysts are classified as infundibular, isthmus-catagen, matrical and hybrid, based on the type of lining epithelium indicative of the origin of the cyst (Scott and others 2001, Gross and others 2006). In particular, infundibular cysts are characterised by squamous epithelium with an evident granular layer, and arise from the infundibulum of the hair follicle (Gross and others 2006). Very few reports of multiple/disseminated follicular cysts have been described in species including dogs, alpacas, sheep, pet birds, horses and human beings (Scott and others 2001, Ginel and others 2007, Ginn and others 2007, Newkirk and Frank 2011).

This case series describes the development of disseminated infundibular cysts in five dogs and one cat. The term ‘disseminated’ is preferred over ‘multiple’ to better describe the presence of multifocal lesions involving the entire body.

The cases enrolled in this series are characterised by a history of progressive development of multiple cutaneous cysts over the entire body. Cases 1–4 were presented to the Veterinary Teaching Hospital (VTH), while cases 5 and 6 were submitted to the diagnostic laboratory for histopathological evaluation only. See Table 1 for the signalment for each case.

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​Case signalment table

Historical information revealed that the first lesions were noticed as single to …

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  • Provenance: Not commissioned; externally peer reviewed

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