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Modifications of some acute phase proteins and the white blood cell count in thoroughbreds during training
  1. F. Fazio, DVM, PhD1,
  2. A. Assenza, DVM, PhD1,
  3. F. Tosto, DVM1,
  4. S. Casella, BSc, PhD1,
  5. G. Piccione, DVM1 and
  6. G. Caola, BCH1
  1. 1 Department of Experimental Sciences and Applied Biotechnology, Faculty of Veterinary Medicine, Polo Universitario Annunziata, University of Messina, 98168 Messina, Italy
  1. E-mail for correspondence: francesco.fazio{at}


The concentrations of plasma fibrinogen and serum haptoglobin and the white blood cell count (WBC) were assessed in 17 thoroughbreds. All horses were trained for 80 days, six days a week, with one day of rest per week. Blood samples were collected from each animal by jugular venepuncture, at 06.00, every 20 days for a period of 80 days, and the fibrinogen and haptoglobin concentrations and WBC were determined. One-way repeated measures analysis of variance, followed by the Bonferroni test, was used to determine significant differences. Training was associated with a significant increase in the concentrations of plasma fibrinogen (Plt;0.01) and serum haptoglobin (Plt;0.0005), but had no significant effect on the WBC count.

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