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Effect of a saline chaser for contrast enhancement of computed tomographic angiography in cattle
  1. K. Lee, DVM1,
  2. M. Kishimoto, DVM, PhD1,
  3. J. Shimizu, DVM1,
  4. T. Iwasaki, DVM, PhD2,
  5. Y. Miyake, DVM, PhD1 and
  6. K. Yamada, DVM, PhD1
  1. 1Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
  2. 2Department of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan
  1. E-mail for correspondence: kyamada{at}


Computed tomographic angiography was performed on nine normal Holstein calves in a crossover method to investigate the effect of a saline chaser for enhancement of the maxillary arteries and dorsal sagittal sinus. One group was administered a contrast injection (600 mg iodine/kg at 4 ml/s) followed by 50 ml of a saline chaser at the same rate as the contrast material. The second group was administered a contrast injection without a saline chaser. Addition of the saline chaser to the contrast material resulted in a higher peak attenuation in the maxillary artery (244.45 ± 36.19 v 202.20 ± 27.07, P<0.05) and dorsal sagittal sinus (241.2 ± 31.51 v 198.88 ± 21.09, P<0.05). These results indicate that a contrast injection followed by saline chaser increased uptake in contrast-enhanced CT.

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