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Mechanical ventilation of six dogs anaesthetised with isoflurane or sevoflurane delivered by a Komesaroff anaesthetic machine
  1. F. G. Laredo, BVSc, PhD, CertVA, MRCVS1,
  2. E. Belda, BVSc, PhD1 and
  3. M. Escobar, BVSc1
  1. 1 Departamento de Medicina y Cirugía Animal, Universidad de Murcia, Campus de Espinardo, 30100 Espinado, Murcia, Spain
  1. laredo{at}


After intravenous induction, six beagles were connected to a Komesaroff machine provided with a single in-circuit vaporiser and ventilated mechanically at either nine or 14 breaths/minute while anaesthetised with either isoflurane or sevoflurane. The vaporiser was initially set at position 4/4 (fully open) and the anaesthetic concentrations were measured after one and five minutes; the vaporiser was then set at the lowest setting able to maintain anaesthesia. Cardiorespiratory variables were measured throughout the study. In most cases anaesthesia was maintained at setting 1/4 with isoflurane and at setting 1.5/4 or 2/4 with sevoflurane.

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