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Pathogenesis of Aeromonas hydrophila strain KJ99 infection and its extracellular products in two species of fish
  1. A. Rey, BVM, MSc1,
  2. N. Verján, BVM&Z, MSc, PhD2,
  3. H. W. Ferguson, BVM&S, PhD, DipACVP, FRCPath, MRCVS3 and
  4. C. Iregui, BVM, DVM1
  1. 1 Laboratory of Pathology, Faculty of Veterinary Medicine, National University of Colombia, Bogotá, Colombia
  2. 2 Laboratory of Genome Science, Tokyo University of Marine Science and Technology, Konan, 4-5-7 Minato, Tokyo 108-8477, Japan
  3. 3 Institute of Aquaculture, University of Stirling, Stirling FK9 4LA
  1. alreyc{at}


The distribution of antigen and pathological changes induced by an experimental infection with Aeromonas hydrophila strain KJ99, and its extracellular products, were studied in two species of fish. The microorganism was disseminated systemically and the haemodynamic and tissue changes were similar to those observed in septicaemia of mammals. Intussusception, degeneration and necrosis of the nervous plexus and muscular layers of the gastrointestinal tract were common findings.

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