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Urinary protein:creatinine ratio in rabbits in relation to their serological status to Encephalitozoon cuniculi
  1. B. Reusch, BVetMed, CertZooMed, MRCVS1,
  2. J. K. Murray, BScEcon, MSc, PhD2,
  3. K. Papasouliotis, DVM, PhD, DipRCPath, DipECVCP, MRCVS2 and
  4. S. P. Redrobe, BSc, BVetMed, CertLAS, DZooMed, MRCVS1
  1. 1 Veterinary Department, Bristol Zoo Gardens, Bristol BS8 3HA
  2. 2 School of Clinical Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU
  1. E-mail for correspondence: brigitte.reusch{at}


The concentrations of protein and creatinine were measured in urine samples from 74 healthy domestic pet rabbits, 54 of them seronegative to Encephalitozoon cuniculi and 20 seropositive. The calculated reference range for the urinary protein:creatinine ratio (UPC) of E cuniculi-seronegative rabbits was 0·11 to 0·40. There was no significant variation in the UPC due to the bodyweight, breed, sex, neutered status or husbandry of the rabbits. Seroconversion to E cuniculi was not found to be associated with clinical renal disease because none of the seropositive rabbits had azotaemia or proteinuria.

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  • Miss Reusch’s present address is Hospital for Small Animals, Easter Bush Veterinary Centre, University of Edinburgh EH25 9RG

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