Two privately owned domestic skunks (Mephitis mephitis) developed clinical signs of hyperparathyroidism. Survey radiographs, complete blood counts and biochemical profiles, including the concentrations of ionised calcium, parathyroid hormone and 25-(OH)-vitamin D, established that they were deficient in vitamin D and had secondary nutritional hyperparathyroidism. They both responded to treatment, as well as to changes in their diet, and levels of exercise and exposure to sunlight.
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