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Isoflurane to prolong medetomidine/ketamine anaesthesia in six adult female chimpanzees (Pan troglodytes)
  1. W. A. Adams, BSc, BVSc, PhD, MRCVS1,
  2. K. J. Robinson, BVSc, MRCVS1,
  3. R. S. Jones, MVSc, DrMedVet, FIBiol, FRCVS1 and
  4. S. Sanderson, MA, VetMB, MRCVS, Chester Zoo2
  1. 1 Department of Anaesthesia, University of Liverpool, The Duncan Building, Daulby Street, Liverpool L69 3GA
  2. 2 Upton by Chester, Chester CH2 1 LH
  1. Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA


Six adult female chimpanzees (Pan troglodytes) were anaesthetised for the placement of intrauterine contraceptive devices, microchips for identification, routine blood sampling, and physical measurements. Anaesthesia was induced with medetomidine in combination with ketamine administered by intramuscular injection with a projectile syringe. Induction was smooth and rapid, but five of the animals were insufficiently relaxed for orotracheal intubation. The plane of anaesthesia was deepened by administering isoflurane delivered in oxygen and nitrous oxide, and general anaesthesia was maintained for up to 74 minutes. The action of medetomidine was reversed at the end of each procedure with atipamezole, and the animals recovered smoothly and uneventfully.

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