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Treatment of canine pyoderma with co-amoxyclav: a comparison of two dose rates
  1. D. H. Lloyd, PhD, BVetMed, FRCVS, DipECVD1,
  2. D. N. Carlotti, DVM, DipECVD2,
  3. H. J. Koch, DVM, DipECVD3 and
  4. A. H. Van Den Broek, BVSc, FRCVS, DVR4
  1. 1 Dermatology Unit, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield AL9 7TA
  2. 2 100 Avenue de l'Aquitaine, 33560 Sainte Eulalie/Bordeaux, France
  3. 3 Tierklinik am Schonenwald, 6588 Birkenfeld, Germany
  4. 4 Department of Veterinary Clinical Studies, University of Edinburgh, Easter Bush, Roslin, Midlothian EH25 9RG


The efficacy of oral co-amoxyclav, administered twice daily for up to 12 weeks either at the manufacturer's dose rate of 12.5 mg/kg or at 25.0 mg/kg, in curing the lesions of canine foiliculitis, furunculosis and celiulitis was compared in a blind study. A total of 97 dogs entered the trial and 67 completed it. There was no significant difference in the rate of cure or the duration of therapy. The lesions of folliculitis were cured in 91 5 per cent of cases, in a mean period of 25.3 days. Furunculosis and celiulitis were cured respectively in 87.5 per cent and 60.0 per cent of the dogs, in mean periods of 37.6 and 44.7 days. The standard dose rate was very effective in folliculitis and furunculosis and there was no benefit in doubling the dose. Too few cases of cellulitis were treated to provide a reliable dose comparison.

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