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Pergolide treatment for Cushing's syndrome in a horse
  1. M. C. Muñoz, DVM, PhD1,
  2. F. Doreste, DVM1,
  3. O. Ferrer, DVM, PhD1,
  4. J. González, DVM1 and
  5. J. A. Montoya, DVM, PhD1
  1. 1 Departamento de Patología Animal, Facultad de Veterinaria de la Universidad de Las Palmas de Gran Canaria, C/Fco Inglott Artiles, 12-A, 35016 Las Palmas de Gran Canaria, Spain


A 16-year-old, male, Hanoverian horse had a three-month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid-releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and benefical clinical and biochemical responses were observed within one to six months.

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