Article Text

Virulence and genotype of a bovine herpesvirus 1 isolate from semen of a subclinically infected bull
  1. JT van Oirschot,
  2. FA Rijsewijk,
  3. PJ Straver,
  4. RC Ruuls,
  5. J Quak,
  6. A Davidse,
  7. F Westenbrink,
  8. AL Gielkens,
  9. JE van Dijk and
  10. A Moerman
  1. Institute for Animal Science and Health, Lelystad, The Netherlands.


A bovine herpesvirus 1 (BHV-1) isolate from the semen of a subclinically infected bull was administered to cattle by various routes to assess its virulence. Cattle that were artificially inseminated or inoculated intrapreputially did not develop clinical signs, but did transmit the virus to contact cattle. However, the isolate induced severe signs of rhinotracheitis and vulvovaginitis in cattle that were inoculated by the intravaginal, intranasal or intravenous routes, but did not infect the fetus. The isolate was therefore not of low virulence. Analysis with DNA restriction enzymes could not assign the isolate to either the BHV-1.1 or BHV-1.2 genotype.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.