Meticillin-resistant Staphylococcus aureus (MRSA) clonal complex (CC) 398 is a genetic lineage associated with livestock, especially pigs. The authors investigated the role of pig trade in the transmission of MRSA CC398 between farms using pulsed-field gel electrophoresis (PFGE), a highly discriminatory method for strain typing. PFGE analysis of 58 MRSA isolates from a retrospective study in the Netherlands and a prospective study in Denmark provided molecular evidence that the strains present in five of the eight recipient farms were indistinguishable from those occurring in the corresponding supplying farm. The molecular typing data confirm the findings of a previous risk-analysis study indicating that trading of colonised pigs is a vehicle for transmission of MRSA CC398.
]]>Various reproductive tract pathological lesions have been reported in non-human primates (NHPs). Congenital abnormalities occur with a similar incidence to the human being, affecting 0.3 to 0.9 per cent of births (
Orf, a viral disease which causes proliferative skin lesions around the mouths of lambs and on the teats of ewes, has long been assumed to have production-limiting consequences. This case-control study involved the collection of data from naturally occurring outbreaks of orf in young lambs on eight commercial farms in north-east England. Measurements of weight were taken and orf lesions were scored on a numerical scale for 44 orf-affected lambs, matched to unaffected controls within the same group. Data from corresponding ewes were available from five farms. Paired t tests showed that affected lambs weighed approximately 10 per cent less than their unaffected controls for a period of at least five weeks following the start of the outbreak. The effects were highly significant whether the orf lesions affected the mouth or were found elsewhere on the body. If a lamb had orf, then there was a 82 per cent chance that its mother also had orf on its udder or teats. The financial consequences of orf in young lambs were estimated using average UK figures and conservative assumptions based on the results of this study.
]]>The urethral fold of 30 mares was split transversely into dorsal and ventral shelves, and the ventral shelf was used to help create a urethral extension. The dorsal shelf was stretched caudally and sutured to the roof of the extension so that it covered at least the cranial half of the extension. For 20 mares, a relaxing, vaginal incision was created cranial to the external urethral orifice to enable the dorsal shelf to be retracted further caudally. Ten of the 30 mares (33.3 per cent) developed a defect, but none developed a defect in that portion covered by the dorsal shelf of the urethral fold. Two of the 30 mares (6.7 per cent) developed a defect so small that the defect could be detected only by inserting a dye, under pressure, into the tunnel. The total number of mares that developed only a grossly visible and palpable defect was eight of 30 (26.6 per cent). Four of the 10 mares that did not receive the relief incision and six of 20 mares that did receive the relief incision developed a defect in the extension. Modifying the McKinnon technique by transversely splitting the urethral fold and retracting the dorsal half helps prevent a defect from forming in the cranial portion of the extension. The dorsal shelf can be retracted further caudally by creating a relief incision on the floor of the vagina.
]]>A questionnaire was sent to 2951 mixed and small animal veterinary practices to examine the use of perioperative antimicrobials in cats and dogs in the UK. The percentage of respondents who always used antimicrobials in two surgical procedures classified according to NRC criteria as ‘clean’ was 25.3 per cent for removal of a 1 cm cutaneous mass and 32.1 per cent for routine prescrotal castration. Factors considered important in decision-making about when to use antimicrobial agents included immunosuppression, presence of a drain, degree of wound contamination, potential for spillage of visceral contents and implantation of prosthesis. The most common antimicrobial agents mentioned were potentiated amoxicillin (98.0 per cent), amoxicillin (60.5 per cent), clindamycin (21.8 per cent), enrofloxacin (21.7 per cent), cephalexin (18.6 per cent) and metronidazole (12.7 per cent). Forty-three per cent of all responding veterinarians listed a long-acting preparation for perioperative use. The routes used were subcutaneous (76.1 per cent), intravenous (25.8 per cent), intramuscular (19.8 per cent), oral (13.5 per cent) and topical (7.7 per cent). Antimicrobials were given before surgery (66.6 per cent), during surgery (30.2 per cent), immediately after surgery (12.0 per cent) and after surgery (6.3 per cent). This survey has identified the suboptimal use of perioperative antimicrobials in small animal surgery with improvements needed with respect to timing, duration, choice of antimicrobial and a more prudent selection of surgical cases requiring prophylaxis.
]]>A case-control study was designed to test whether there is an association between the owners seeing the mother of a puppy, and later development of behavioural problems. The sample consisted of dogs that were seen by animal behaviourists (members of the Association of Pet Behaviour Counsellors) and equivalent dogs (without a behavioural problem, but the owners would consider referral to an animal behaviourist were the dog to develop a behavioural problem) seen at a veterinary practice that referred to each animal behaviourist. After adjustment for confounding factors using multivariable logistic regression, case dogs were more likely to be younger than controls (P<0.001); less likely to be obtained at six (OR=0.27, 95 per cent CI=0.09 to 0.85, P=0.03), nine (OR=0.22, 95 per cent CI=0.06 to 0.80, P=0.02) or 10 weeks (OR=0.35, 95 per cent CI=0.12 to 1.01, P=0.05), than eight weeks; more likely for the owner to have seen only one parent (OR=2.49, 95 per cent CI=1.15 to 5.37, P=0.02) than both parents, and more likely to have not seen either parent (OR=3.82, 95 per cent CI=1.12 to 12.97, P=0.03) than both. Advice to ‘see the mother’ has been shown to be partly scientifically accurate in relation to future unwanted behavioural problems among dogs; in fact, it may be better for prospective owners to be recommended to view both parents.
]]>The herd was an organic 100...]]>
Six cases of rostral mandibular fracture with considerable displacement were treated successfully by external coaptation. Four cases were simple and two were compound fractures. After xylazine sedation and manual reduction of the fractures, the casting tape was laminated to make a rigid splint below the mandibles and then the splint was secured using the casting tape passing the nasal bridge and cranial and/or caudal to the ears as it encircled the head. During application of the tape, a PVC pipe 25 mm in diameter was held in its jaws to keep the mouth open so that the calf could suckle. Simple rostral mandibular fractures were cured after two weeks of cast immobilisation and compound fractures after about three weeks. This method is easy and non-stressful and provided a good prognosis in the present cases.
]]>The severity of clinical signs, the typically advanced age of the dog and the likelihood of malignant neoplasia inevitably results in euthanasia based on a presumptive diagnosis in a large proportion of cases (
From 1998 to 2006, five different BTV serotypes (1, 2, 4, 9 and 16) have spread throughout extensive portions of Mediterranean Europe (
To limit direct losses and in an effort to minimise the circulation of BTV and allow safe movements of animals, authorities from affected European countries undertook vaccination of livestock with inactivated BTV-8 and BTV-1...]]>
The aim of this study was to quantitatively assess the kind of transport dogs undergo, the behaviours displayed during transport, the prevalence of travel-related problems in dogs and owners' interventions to solve these problems. A convenience sample of 907 dog owners completed a questionnaire containing 16 multiple-choice questions. All dogs had been transported by car at least once, but 4.7 per cent were no longer transported. 76.2 per cent of animals always responded positively to car transport, the rest showing or having shown problems (6.7 per cent always reacted negatively). Dogs were found to be more excited than inhibited during car transport. The vast majority (86.0 per cent) had become used to travelling by car as puppies; this made them less likely to develop problems (6.3 per cent v 24.1 per cent; 2=19.886, P=0.000). If dogs were transported only to veterinary clinics, they were more prone to respond negatively to car transport (46.4 per cent v 22.7 per cent; 2=7.245, P=0.007). For dogs reported as problematic (23.8 per cent of the sample), 96.3 per cent of the owners did not administer any treatments or other substances, 48.7 per cent did not seek any advice, and 40.4 per cent of them made attempts to solve the problem by themselves.
]]>Deslorelin acetate implants, recently licensed in Ireland and the UK for ovulation induction in mares, have been associated with prolonged interovulatory intervals in USA studies, leading to the practice of removing implants postovulation. Trial data in Australia indicate a less pronounced effect on interovulatory intervals, suggesting possible geographical variation. Objectives of the current study were to assess the effect of deslorelin implants, with and without removal on oestrous cycle length in Irish- and UK-based Thoroughbred broodmares. Data were collected retrospectively from 88 oestrous cycles. A statistically significant difference (P=0.02) was found between interovulatory intervals in mares in which the deslorelin implant was not removed, compared with administration and removal of the implant or the use of human chorionic gonadotrophin. The results suggest that implant removal when possible is advisable. The delay in subsequent ovulations was less marked than that reported in some studies from the USA. This information is useful in deciding when to schedule subsequent breeding for mares which received a deslorelin implant during the previous oestrous period and provides evidence to counter-concerns that mares treated with deslorelin implants may experience a long delay in return to oestrus if the implant is not removed.
]]>The ‘Singleton Protocol’ was adopted by the Irish Department of Agriculture Fisheries and Food (DAFF) in 1996 to address the incomplete specificity of the single intra-dermal comparative tuberculin test (SICTT) used in Ireland for the detection of animals infected with bovine tuberculosis (bTB). The protocol allows the early restoration of disease-free status to herds with a single reactor breakdown, where the herd was not confirmed as infected with Mycobacterium bovis by epidemiological investigation, by postmortem examination or by further test. The current study examines the ability of the Singleton Protocol to identify false-positive reactors. It investigates the subsequent herd-reactor rate following single reactor removal and analyses the factors leading to a positive postmortem lesion outcome and a positive reactor retest result. Postmortem lesion results were obtained for 371 reactor animals from single reactor breakdowns that were killed at an export meat plant over a 19-month period. Epidemiological and test data for these animals and their herds were obtained from DAFF databases and analysed by univariate and multivariate statistical analysis. Singleton candidates had an 18.7 per cent lower lesion rate than single animal breakdowns not meeting the singleton criteria. No significant difference was found between Singletons and non singletons in the subsequent reactor retest results. Skin thickness at the SICTT is the most significant determinant of a positive lesion result. The area bTB history was shown to be a significant variable in producing a positive reactor retest result.
]]>A number of different haemoplasma species have been described in cattle: Eperythrozoon wenyonii (
In two abattoirs, visual cleanliness of 100 cattle was assessed before slaughter (on a scale of 1 to 4). From each animal, two sponge swabs (approximately 2000 cm2 area, each) were taken: (a) from hide, immediately after sticking, and (b) from final carcase, but before chilling. In each swab sample, total viable count (TVC), Enterobacteriaceae count (EC) and the presence of Escherichia coli O157 were determined. The mean TVC/EC status of hides and final carcases differed significantly only between very dirty cattle (category 4) and all other less dirty or clean cattle (categories 1, 2 and 3), but not between the less dirty and clean cattle (between categories 1, 2 and 3). However, no clear relationship between the visual cleanliness of the hide and the occurrence of E coli O157 on hide or dressed carcases was observed. The study indicated the possibility that visual categorisation of cattle into only two main categories – one containing very dirty animals (category 4 in this work, corresponding to categories 4+5 in The UK Food Standards Agency system) and another containing all the other less dirty or clean animals (categories 1+2+3) – could be sufficient in practice.
]]>The occurrence of five periparturient events and their effects on subsequent culling and fertility was recorded in eight herds in the UK. Combining data from all 2105 calvings, the proportion affected by assisted calving, dead calf, retained fetal membranes (RFM), milk fever or twins was 5.9, 8.2, 5.3, 5.0 or 3.3 per cent, respectively. Compared with unaffected herdmates, cows with an assisted calving or a dead calf had higher early (but not late) culling rates, (assisted calving: 8.8 per cent being culled before 100 days after calving compared with 5.7 per cent; P=0.05; dead calf: 12.2 per cent culled compared with 5.3 per cent; P=0.001). Compared with unaffected animals, cows with milk fever were four times more likely to be culled before 100 days after calving (16.2 per cent compared with 5.3 per cent; P=0.001), whereas those with RFM were twice as likely to be culled between 100 and 200 days (14.3 per cent compared with 7.6 per cent; P=0.003), and both groups were twice as likely to not be pregnant by 200 days. Cows with RFM or milk fever also had markedly reduced subsequent fertility: both conditions extended calving to pregnancy intervals (by 20 days; P=0.001, or by 13 days; P=0.03, respectively), lowered 100-day in-calf rates (by 24.5 per cent; P=0.001, or by 17.8 per cent; P=0.008, respectively) and lowered 200-day in-calf rates (by 20 per cent; P=0.001, or by 15 per cent; P=0.002, respectively). The birth of twins had no effect on subsequent culling or fertility.
]]>Fluoroquinolones are antimicrobial drugs which generally have very good activities against a broad spectrum of aerobic bacteria, including Pasteurella species, and mycoplasma (
Laryngeal saccule eversion has been widely reported as an important component of brachycephalic airway obstructive syndrome (BAOS). The authors hypothesised that saccules affected by acute histological changes in patients showing marked improvement following palate and nares surgery might spontaneously return to normal; moreover, spontaneous resolution of the eversion in patients with fibrotic saccules and/or without clinical improvement following BAOS surgery might be impossible and, on the contrary, the persistence of turbulent airflow and associated ongoing inflammation might lead to aberrant tissue proliferation after resection. In order to demonstrate our hypotheses, the authors decided to perform a unilateral sacculectomy and to postpone and assess the need for the execution of the contralateral saccule resection according to the findings of a second-look laryngoscopy. Ten dogs were enrolled. None of the saccules left in situ underwent spontaneous resolution of the eversion. In one dog, after sacculectomy, proliferation of a soft tissue lesion endoscopically similar to a newly formed saccule occurred. The results of the present study suggest that spontaneous resolution of saccule eversion is uncommon, even after the correction of the primary abnormalities (palate, nares). Resection of the saccules can relieve ventral rima glottidis obstruction; however, secondary intention healing might occasionally result in the recurrence of the obstruction
]]>Yorkshire terriers may be prone to respiratory disease; however, limited epidemiological information is available. A cross-sectional study design was used to compare the prevalence of respiratory signs in Yorkshire terriers with the prevalence in a population of dogs in general and to identify risk factors for respiratory clinical signs within the Swedish population of Yorkshire terriers. Data on clinical signs and risk factors were obtained from a questionnaire. The prevalence of respiratory signs in general (RS) was significantly higher among Yorkshire terriers compared with control dogs (RS 56.3 per cent and 23.0 per cent), and likewise more frequent respiratory signs (FRS) (26.0 per cent and 5.0 per cent). Age, sex and breed were shown to be significant risk factors, and an interaction between age and sex was discovered. The study indicated a sex ratio reversal in the prevalence of RS – the probability of females having RS increased with advancing age, while the probability for males was fairly constant.
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