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Leptospirosis acquisition following the reintroduction of wildlife
  1. M. Gelling, MSc DPhil CEcol MCIEEM1,
  2. W. Zochowski, MA (Dist), FIBMS, CSci2,
  3. D. W. Macdonald, MA (Oxon) DPhil DSc1,
  4. A. Johnson, MBChB, MSc, FRCPath2,
  5. M. Palmer, MSc2 and
  6. F. Mathews, BA MA DPhil3
  1. 1WildCRU, University of Oxford, The Recanati-Kaplan Centre, Tubney House, Abingdon Road, Tubney, Oxon, Oxford OX13 5QL, UK
  2. 2Leptospira Reference Unit, Department of Microbiology and Immunology, County Hospital, Stonebow Road, Hereford HR1 2ER, UK
  3. 3Department of Biosciences, College of Life and Environmental Sciences, University of Exeter, Hatherley Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK
  1. E-mail for correspondence: merryl{at}siliconspires.co.uk

Abstract

Potential risks posed to domestic animals and human beings by zoonotic diseases in reintroduced animals can reduce the acceptability of reintroductions. The authors investigated the role of endangered water voles, Arvicola amphibius, as a host for leptospirosis, a waterborne zoonosis affecting a range of mammals. Based on samples from 112 individuals from across the UK, a 6.2 per cent exposure rate was found (7 animals were microscopic agglutination test (MAT) positive for serum antibodies), with 4 of 11 sites having positive animals. No individual was actively excreting leptospires in urine (PCR urine test, 0 per cent positive). The acquisition of Leptospira species by a cohort of ‘clean’ captive-bred voles reintroduced to one site in the wild was then examined. By four months postrelease the maximum exposure prevalence (by either MAT or culture) was 42.9 per cent. Thirty-five per cent were actively excreting leptospires. The rapidity of leptospire acquisition and comparatively high prevalence of infectious individuals is notable, exceeding expectation based on wild voles. One possible explanation is a lack of immunocompetence in reintroduced voles. Analyses of haematological parameters from reintroduced voles suggest a link between prior condition and disease acquisition. There may be potential to select the fittest animals before release to maximise reintroduction success.

  • Arvicola amphibius
  • Disease
  • Immunocompetence
  • Leptospirosis
  • Pathogen
  • Reintroduction
  • Accepted September 27, 2015.

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