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Anti-Müllerian hormone: a potential biomarker for differential diagnosis of cryptorchidism in dogs
  1. F. Gharagozlou, DVM, DVSc1,
  2. R. Youssefi, DVM1,2,
  3. V. Akbarinejad, DVM3,
  4. N. I. Mohammadkhani, BSc1 and
  5. T. Shahpoorzadeh, DVM1
  1. 1Department of Theriogenology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  2. 2Theriogenology Association, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  3. 3Young Researchers and Elites Club, North Tehran Branch, Islamic Azad University, Tehran, Iran
  1. E-mail for correspondence: v_akbarinejad{at}ut.ac.ir

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Cryptorchidism, in which the testes fail to descend into the scrotum by six months of age, is a developmental disorder in male dogs (Johnston and others 2001). Cryptorchidism predisposes the animal to testicular neoplasia, therefore the retained testes should be surgically removed for the health of the animal (Johnston and others 2001). Hence, when deciding whether to perform surgery, it is diagnostically essential that cryptorchidism be differentiated from other conditions in which the testes are not present in the scrotum, including anorchidism or cases that have been castrated (England and others 1989; Johnston and others 2001).

Anti-Müllerian hormone (AMH) is produced by Sertoli cells in different species of mammals, including dogs, and plays a crucial role in sexual differentiation; that is, AMH induces the regression of the paramesonephric ducts during the early embryonic development in …

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