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Prevalence of torque teno virus infection in pig herds in China
  1. X. Liu, MSc,
  2. W. Gu, MSc,
  3. X. Guo, PhD,
  4. X. Ge, PhD,
  5. Y. Chen, BSc and
  6. H. Yang, PhD
  1. Key Laboratory of Zoonosis, Ministry of Agriculture, College of Veterinary Medicine, and State Key Laboratory for Agrobiotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, China
  1. Correspondence to Dr Yang, e-mail: yanghanchun1{at}cau.edu.cn

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TORQUE teno virus (TTV) is recognised as a small, non-enveloped virus containing a single-stranded, negative-sense, circular DNA genome (Okamoto and others 1998, Mushahwar and others 1999). The agent was originally discovered in the plasma of a Japanese patient with a post-transfusion non-A to G hepatitis infection in 1997 and was designated TT virus based on the patient's initials (Nishizawa and others 1997). In 2005, the International Committee on Taxonomy of Viruses classified TTV into the ‘floating’ genus Anellovirus of Circoviridae, suggesting the new and present name for TTV (Kekarainen and Segalés 2009). Despite being a DNA virus, the sequences of human TTV are extraordinarily diverse, spanning five groups and 34 genotypes (Biagini and others 2006, Kekarainen and Segalés 2009). Recently, much attention has been paid to TTV infection in other species (Okamoto and others 2002, Okamoto 2009), especially pigs (McKeown and others 2004, Bigarré and others 2005, Sibila and others 2009). Based on the genomic sequences of TTV, porcine TTV is classified into two distinct genogroups: TTV type 1 (TTV-1) and TTV-2 (Okamoto and others 2002, Niel and others 2005, Brassard …

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