Article Text

other Versions

PDF
Effect of cross-fostering on transfer of maternal immunity to Mycoplasma hyopneumoniae to piglets
  1. M. Bandrick, BS, PhD1,
  2. M. Pieters, DVM, PhD1,
  3. C. Pijoan, DVM, PhD1,
  4. S. K. Baidoo, PhD2 and
  5. T. W. Molitor, PhD1
  1. Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
  2. Southern Research and Outreach Center, University of Minnesota, Waseca, MN 56093, USA
  1. Correspondence to Dr Molitor: molit001{at}umn.edu
  • Dr Pieters's present address is Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA

The aim of this study was to assess the effect of cross-fostering on transfer of maternal Mycoplasma hyopneumoniae-specific humoral and cell-mediated immunity (CMI) from gilts to piglets. Cross-fostering, carried out within gilt pairs, was based on the gilts' M hyopneumoniae vaccination status in accordance with the following scheme: six pairs of vaccinated gilt × non-vaccinated gilt (V × N); five pairs of non-vaccinated gilt × vaccinated gilt (N × V); and five pairs of vaccinated gilt × vaccinated gilt (V × V). The piglets were cross-fostered at 0, six, 12 or 20 hours after birth. Two piglets per gilt per time point were cross-fostered (that is, eight piglets per gilt were moved) and the remaining piglets served as non-cross-fostered controls. In addition, four litters served as non-cross-fostered controls. A maximum of 10 piglets per gilt were sampled. The piglets' M hyopneumoniae-specific humoral immunity was assessed by ELISA and their CMI was assessed by delayed-type hypersensitivity testing. M hyopneumoniae-specific antibodies were detected in non-cross-fostered piglets from vaccinated dams and from piglets cross-fostered within the V × N gilt pair at six hours or more, and within the V × V gilt pair at all time points. Piglets cross-fostered within the N × V gilt pair had detectable M hyopneumoniae-specific antibodies only if they had been moved within six hours of birth. The transfer of M hyopneumoniae-specific CMI to piglets appeared to be source-dependent, and was detected only in piglets maintained on their vaccinated dams for at least 12 hours after birth.

Statistics from Altmetric.com

Footnotes

  • Dr Pijoan died in 2007

  • Provenance not commissioned; externally peer reviewed

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.