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Systematic review of anti-epileptic drugs in cats

M. Charalambous, A. Pakozdy and others

BMC Veterinary Research (2018) 14, 64

doi: 10.1186/s12917-018-1386-3

• What did the research find?

The systematic review found that evidence on feline epilepsy treatment is weak to absent.

Using the limited data available, the results showed that phenobarbital was considered the most effective anti-epileptic drug (AED), followed by levetiracetam and potassium bromide, then imepitoin and diazepam. Regarding the safety profile of AEDs, imepitoin was considered the safest AED, followed by levetiracetam and phenobarbital.

Overall, assessments of the efficacy and safety profile of AEDs indicated that phenobarbital should be used as the first-choice AED, followed by imepitoin and levetiracetam.

• How was it conducted?

PubMed, CAB Direct and Google Scholar were searched to detect peer-reviewed studies reporting on the efficacy and/or adverse effects of AEDs in cats.

Studies were assessed with regards to their quality of evidence (study design, study population, diagnostic …

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