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Obese dogs have altered cardiac and metabolic variables
M. Tropf, O. L. Nelson, P. M. Lee, H. Y. Weng
AS obesity is becoming more prevalent in dogs, determining the effects of obesity on cardiovascular function and whether obesity can have additive effects on the development of cardiac disease in dogs is imperative.
This study aimed to evaluate cardiac structure and function and metabolic variables in obese dogs compared to ideal weight dogs.
Healthy small breed (<25 pounds) dogs were recruited. Comparisons were made between 29 obese dogs and 17 with ideal body composition. Cardiac structure and function were determined by standard and strain echocardiographic measurements and quantification of serum metabolic variables (insulin:glucose ratios, lipid analysis, adiponectin and inflammatory markers).
Compared to the ideal weight controls, obese dogs had cardiac changes characterised by an increased interventricular septal width in diastole to left ventricular internal dimension in diastole ratio, decreased ratios of peak early to peak late left ventricular inflow velocities, and ratios of peak early to peak late mitral annular tissue velocities, and increased fractional shortening and ejection fraction percentages. Obese dogs had metabolic derangements characterised by increased insulin:glucose ratios, …