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Quantitative analysis of antibiotic usage in British sheep flocks
  1. Peers Davies, MA VetMB PhD MRCVS1,
  2. John G Remnant, BVSc CertAVP FHEA DipECBHM MRCVS1,
  3. Martin J Green, BVSc DCHP PhD DipECBHM MRCVS1,
  4. Emily Gascoigne, MA VetMB MRCVS2,3,
  5. Nick Gibbon, BVSc MRCVS4,
  6. Robert Hyde, BVM BVS MRCVS1,
  7. Jack R Porteous, BVM BVS MRCVS5,
  8. Kiera Schubert, MA VetMB CertAVP MRCVS6,
  9. Fiona Lovatt, BVSc DSHP PhD DipECSRHM MRCVS1 and
  10. Alexander Corbishley, MA VetMB PhD FHEA MRCVS7,8
  1. 1School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK
  2. 2Synergy Farm Health LTD, West Hill Barns, Evershot, Dorchester, UK
  3. 3RAFT Solutions Ltd, Mill Farm, Ripon, UK
  4. 4Belmont Farm & Equine Ltd, Hereford, UK
  5. 5Browne & McKinney, Broughton-in-Furness, UK
  6. 6Torch Farm and Equine, Bideford, UK
  7. 7Dairy Herd Health and Productivity Service, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, UK
  8. 8Division of Immunity and Infection, The Roslin Institute, The University of Edinburgh, Midlothian, UK
  1. E-mail for correspondence; Peers.Davies{at}nottingham.ac.uk

Abstract

The aim of this study was to examine the variation in antibiotic usage between 207 commercial sheep flocks using their veterinary practice prescribing records. Mean and median prescribed mass per population corrected unit (mg/PCU) was 11.38 and 5.95, respectively and closely correlated with animal defined daily dose (ADDD) 1.47 (mean), 0.74 (median) (R2=0.84, P<0.001). This is low in comparison with the suggested target (an average across all the UK livestock sectors) of 50 mg/PCU. In total, 80 per cent of all antibiotic usage occurred in the 39 per cent of flocks where per animal usage was greater than 9.0 mg/PCU. Parenteral antibiotics, principally oxytetracycline, represented 82 per cent of the total prescribed mass, 65.5 per cent of antibiotics (mg/PCU) were prescribed for the treatment of lameness. Oral antibiotics were prescribed to 49 per cent of flocks, 64 per cent of predicted lamb crop/farm. Lowland flocks were prescribed significantly more antibiotics than hill flocks. Variance partitioning apportioned 79 per cent of variation in total antibiotic usage (mg/PCU) to the farm level and 21 per cent to the veterinary practice indicating that veterinary practices have a substantial impact on overall antimicrobial usage. Reducing antibiotic usage in the sheep sector should be possible with better understanding of the drivers of high usage in individual flocks and of veterinary prescribing practices.

  • antibiotic
  • antimicrobials
  • sheep
  • Amr
  • Addd
  • population corrected unit

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Footnotes

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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