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Toxicology
Raspberry ketone ingestion in dogs
  1. Roxanne MacCallum1,
  2. Nicola Bates2 and
  3. Nick Edwards2
  1. 1Vets4Pets Eastleigh, Woodside Avenue, Eastleigh SO50 9ER
  2. 2Veterinary Poisons Information Service, Godfree Court, 29-35 Long Lane, London SE1 4PL

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RASPBERRY ketone (4-(4-hydroxyphenyl)-2-butanone) has become popular as a weight loss supplement in humans and is often found in multi-ingredient preparations, particularly with caffeine (usually 30 to 200 mg, but the dosage may not be declared on the label).

Raspberry ketone is structurally similar to other naturally occurring botanical compounds (capsaicin and synephrine) and is thought to have sympathomimetic effects. Experimental studies have shown that it alters lipid metabolism in adipocytes (Park 2015) and enhances noradrenaline-induced lipolysis (Morimoto and others 2005). There is limited information on the safety and toxicity …

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