Statistics from Altmetric.com
Is there transmission of colistin-resistant Escherichia coli between companion animals and people?
X-F. Zhang, Y. Doi, X. Huang, H-Y. Li, L-L. Zhong, K-J. Zeng and others
PLASMID-mediated, colistin-resistance mechanism mcr-1 gene was discovered in Escherichia coli isolates from food, food animals and people last year and, following this, there have been reports of mcr-1 detection in Enterobacteriaceae from people and food animals from other countries. This paper reports the detection of mcr-1 in colistin-resistant E coli isolated from companion animals and the possible transmission of mcr-1-harbouring E coli between companion animals and people.
Three mcr-1-harbouring E coli clinical isolates were identified from specimens from three patients admitted to a urology ward of a hospital in Guangzhou, China. These were E coli isolates EC07, EC08 and EC09.
The patient carrying the E coli isolate EC07 was a worker in a pet shop and this led to the researchers collecting 53 faecal samples from 39 dogs and 14 cats from that pet shop. E coli colonies were identified and isolated. Crude DNA samples of isolates were prepared for PCR testing by boiling cells in water. In these samples, six were positive for mcr-1 by PCR and sequencing (from four dogs and two cats). All six isolates were resistant to …