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WHEN considering the use of cardiac biomarkers for diagnosis, prognosis and monitoring of cardiac diseases, is equine cardiology catching up with small animal and human cardiology?
The paper by Van der Vekens and others (2015), summarised on page 624 of this issue of Veterinary Record, presents an initial step towards achieving this goal by testing a new technique to measure plasma proANP concentrations in horses with and without cardiac disease.⇓
Natriuretic peptides, including atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), are hormones synthesised by cardiomyocytes. They play an important role in blood pressure regulation, diuresis and natriuresis. They are also known to increase in response to a cardiomyocytes stretch due to pressure or volume overload, for example, during prolonged strenuous …