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GM2 gangliosidosis (Tay-Sachs disease) in British Jacob sheep was reported in Veterinary Record by Wessels and colleagues (VR, January 4, 2014, vol 174, pp 20-21). These authors described the clinical and pathological findings associated with this disabling disease, which is inherited as an autosomal recessive condition. The exact prevalence of the causal mutation in the UK flock has yet to be determined.
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