rss
Veterinary Record 174:169 doi:10.1136/vr.102046
  • Research
  • Paper

Serial CT features of pulmonary leptospirosis in 10 dogs

  1. J. Lang, Prof Dr.med.vet. Dipl ECVDI1
  1. 1Clinical Radiology Division, VetSuisse Faculty, University of Bern, Bern, Switzerland
  2. 2Department of Diagnostic Radiology, University Hospital of Bern, Inselspital, Bern, Switzerland
  3. 3Internal Medicine Division, Vetsuisse Faculty, University of Bern, Bern, Switzerland
  4. 4Department of Clinical Research & Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland
  1. E-mail for correspondence: karine.gendron{at}vetsuisse.unibe.ch

Abstract

Leptospirosis pulmonary haemorrhage syndrome (LPHS) is a frequent manifestation of Leptospira infection in dogs and is associated with a high morbidity and mortality. Three helical 16-slice thoracic CT scans were performed in 10 dogs naturally infected with Leptospira, within 24 hours of admission, and three and seven days later. Patients were sedated and scanned without breathhold, with a protocol adapted for rapid scanning. One dog died of respiratory failure on the morning following the first scan. On the initial scan, imaging features of LPHS included ground-glass nodules (10/10), peribronchovascular interstitial thickening (10/10), diffuse or patchy ground-glass opacity (9/10), solid nodules (8/10) and consolidation (7/10). Temporary bronchiolar dilation was observed in all dogs in association with peribronchovascular interstitial thickening, which had completely resolved at day 7. Nodules were with few exceptions assigned to the centrilobular region. Regression of lesion severity was observed after each subsequent scan. Consolidation and solid nodules changed over time into lesions of ground-glass attenuation. Pleural effusion (3/10) and mediastinal effusion (2/10) were mild and transient. Lesion severity appeared unassociated with survival to discharge.

  • Accepted December 16, 2013.
  • Published Online First 13 January 2014

Sign up for job alerts

Vet Record Careers features a comprehensive database of vet jobs.
Browse for your next job, or set personalised job alerts so you hear about vacancies as soon as they go online.
Find out more at Vet Record Careers

Free Sample Issue

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of the Veterinary Record.
View free sample issue >>

Navigate This Article