Statistics from Altmetric.com
Anthelmintic properties of Australian plants
S. E. Payne, A. C. Kotze, Z. Durmic, P. E. Vercoe
CYATHOSTOMINS are a common parasite of horses worldwide and can cause the potentially fatal condition larval cyathostomiasis. Traditionally, anthelmintics have been the standard treatment for these parasites, however, this has been compromised during recent years owing to increased resistance among cyathostomin species to the major anthelmintic drug classes, including benzimidazoles and tetrahydropyrimidines. This study aimed to screen a range of Australian plant species for anthelmintic activity against cyathostomins in vitro.
Samples of 37 Australian plants held in a collection at the University of Western Australia were selected based on previous reports indicating that they contained bioactive substances or were palatable to livestock. Cyathostomin eggs were collected from the faeces of infected horses that had not been treated with anthelmintics for at least eight weeks. The plants and their extracts were prepared in the laboratory and then placed on plates with a number of eggs. Control substances included water, ivermectin and levamisole. The samples were incubated and fed over the course of one week. At the end of the incubation period, the number of eggs having reached a certain developmental stage were counted in each sample.
Of the 37 species …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.