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Veterinary Record 172:268 doi:10.1136/vr.100937
  • Research
  • Paper

Arrhythmogenic right ventricular cardiomyopathy in boxer dogs: a retrospective study of survival

  1. J. Manubens, DVM2
  1. 1Faculty of Veterinary Medicine, Medicina y Cirugía Animal, University Complutense of Madrid, Madrid, Spain
  2. 2Department of Cardiology and Respiratory, Hospital Veterinari Molins, Barcelona, Spain
  3. 3Internal Medicine, Faculty of Veterinary Medicine, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Arucas, Gran Canaria, Spain
  1. E-mail for correspondence: aliciac{at}vet.ucm.es

Abstract

The aim of the present study was to retrospectively evaluate survival in a population of 62 boxer dogs with arrhythmogenic right ventricular cardiomyopathy (ARVC), without left ventricular systolic failure, based on the following factors: age at diagnosis, presence of syncopal episodes, Holter arrhythmia classification and administered treatment. Medical records of boxer dogs with a diagnosis of ARVC between 2000 and 2010 were reviewed. Results showed that median survival time (MST) was longer in younger ARVC dogs than in the older ones P<0.001). MST was statistically different (P=0.012) between dogs with syncope (365 days) and dogs without syncope episodes (693 days), the probability of death within a year being 4.8 times greater in dogs with syncope (95% CI 1.48 to 15.99) than in dogs without syncope. Regarding Holter classification results, MST was 547.5 days in Holter class-2 dogs and 365 days in Holter class-4 dogs (P=0.030). There were no differences regarding treatment options; MST was 365 days (95% CI 193.615 to 536.4) in the sotalol group, 365 days (95% CI 92.86 to 637.14) in the mexiletine plus atenolol group, and 547.50 days (95% CI 170.45 to 924.55) in the procainamide group (P=0.383). According to this study, the best prognosis is for the younger boxer dog without syncope. There were no differences in survival times in relation to the different treatment options used.

  • Accepted December 18, 2012.
  • Published Online First 12 January 2013

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