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Risk factors for bovine neonatal pancytopenia in Germany

C. Sauter-Louis, A. Carlinm, A. Friedrich, A. Assad, F. Reichmann, G. Rademacher, C. Heuer, W. Klee

A MARKED increase in the incidence of bovine neonatal pancytopenia (BNP) has been reported since 2006, causing considerable animal health concerns. This case-control study aimed to identify risk factors associated with the observed increase in the numbers of calves showing clinical signs of the disease.

The characteristics of 56 dairy farms in southern Germany with at least one confirmed case of BNP were compared with those of two sets of control farms each with no history of BNP. Information was collected via questionnaires and interviews. The first set of controls was selected randomly from veterinary practices that had never observed a BNP case. The second set of controls was matched by veterinary practices that had provided the BNP case farms. Two separate sets of analyses were conducted: case farms versus random control group and case farms versus matched control group. A complex multivariate statistical approach was used to investigate a large number of putative factors.

Initial univariable analysis showed a positive association of BNP with the use of the bovine viral diarrhoea vaccine PregSure, with …

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