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WE would like to report confirmation of triclabendazole resistance (TCBZ-R) in liver fluke, Fasciola hepatica, from the UK, based on a dose and slaughter trial. Recently, there has been considerable debate regarding the usefulness of reports of triclabendazole treatment failure in liver fluke infected sheep and cattle as an indicator of TCBZ-R (Fairweather 2011, Sargison and Scott 2011). It has been suggested that the diagnosis of TCBZ-R in the field should be based on a combination of diagnostic tests (Fairweather 2011). We used a combination of faecal egg count reduction testing (FECRT) and coproantigen reduction testing (CRT) to demonstrate TCBZ-R in …
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