Article Text

Liver Fluke
Confirmation of triclabendazole resistance in liver fluke in the UK
  1. Danielle Gordon1,
  2. Ruth Zadoks1,
  3. Philip Skuce1 and
  4. Neil Sargison2
  1. 1Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ
  2. 2Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG
  1. e-mail: ruth.zadoks{at}

Statistics from

WE would like to report confirmation of triclabendazole resistance (TCBZ-R) in liver fluke, Fasciola hepatica, from the UK, based on a dose and slaughter trial. Recently, there has been considerable debate regarding the usefulness of reports of triclabendazole treatment failure in liver fluke infected sheep and cattle as an indicator of TCBZ-R (Fairweather 2011, Sargison and Scott 2011). It has been suggested that the diagnosis of TCBZ-R in the field should be based on a combination of diagnostic tests (Fairweather 2011). We used a combination of faecal egg count reduction testing (FECRT) and coproantigen reduction testing (CRT) to demonstrate TCBZ-R in …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.