rss
Veterinary Record 171:527 doi:10.1136/vr.100811
  • Research
  • Papers

Systemic or intrasynovial medication as singular or as combination treatment in horses with (peri-)synovial pain

  1. P. R. van Weeren, DVM, PhD, Dipl. ECVS
  1. Department of Equine Sciences, Faculty of Veterinary Medicine, University of Utrecht, Yalelaan 112-114, Utrecht NL-3584 CM, The Netherlands
  1. E-mail for correspondence: H.Brommer{at}uu.nl

Abstract

Records of lame horses (2004–2007) with (peri-)synovial pain of the metacarpophalangeal joint (MCPJ, n = 53), digital flexor tendon sheath (DFTS, n = 20), and distal interphalangeal joint (DIPJ, n = 31) were evaluated (n = 104). Cases were grouped according to the following treatments: (1) systemic administration of NSAIDs (n = 40); (2) intrasynovial administration of glucocorticosteroids (n = 30); (3) combination treatment (n = 34). Outcome was defined as successful when the owner reported that the horse had returned to its previous level of performance within a period of up to six months after treatment. Statistical evaluation was performed using Fisher's Exact tests and multivariable logistic regression analyses at P < 0.05. Successful outcome was significantly higher for horses in treatment group 3 (19/34, 55.9 per cent, P = 0.021) than in treatment groups 1 (11/40, 27.5 per cent, OR 0.21, 95 per cent CI 0.06 to 0.71) and 2 (8/30, 26.6 per cent, OR 0.18, 95 per cent CI 0.06 to 0.56). A significant association was only found with regard to the affected synovial structure (P = 0.025); relative to the DIPJ, involvement of the MCPJ and DFTS was four to five times more likely to provide a successful outcome (OR 4.18 and 5.59, 95 per cent CI 1.24 to 14.08 and 1.42–22.22, respectively).

  • Accepted September 21, 2012.
  • Published Online First 23 October 2012

Sign up for job alerts

Vet Record Careers features a comprehensive database of vet jobs.
Browse for your next job, or set personalised job alerts so you hear about vacancies as soon as they go online.
Find out more at Vet Record Careers

Free Sample Issue

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of the Veterinary Record.
View free sample issue >>

Navigate This Article