Article Text

PDF
Papers
Changes in prevalence of progressive feline leukaemia virus infection in cats with lymphoma in Germany
  1. K. Meichner, DVM, DECVIM-CA,
  2. D.B. Kruse,
  3. J. Hirschberger, DVM, DECVIM-CA, DECVCP and
  4. K. Hartmann, DVM, DECVIM-CAQ6
  1. Clinic of Small Animal Medicine, Centre of Clinical Veterinary Medicine, Ludwig Maximilian University Munich, Veterinaerstrasse 13, 80539 Munich, Germany
  1. E-mails for correspondence: TinaMeichner{at}gmx.de

Abstract

Progressive infection with feline leukaemia virus (FeLV) is considered one of the major risk factors for development of feline lymphoma. The aim of this study was to compare cats with lymphoma between 1980 and 1994 (first period) and between 1995 and 2009 (second period) concerning FeLV antigenaemia and age distribution. In addition, differences between FeLV antigen-positive and antigen-negative cats with lymphoma regarding patients' characteristics, tumour location and outcome were evaluated. There was a significant decrease in the percentage of lymphoma cases associated with progressive FeLV infection from the first (59 per cent) to the second (13 per cent) observation period. FeLV antigen-positive cats were significantly younger (median 3.7 v 11.3 years), and had significantly shorter response duration (median 25 days v 472 days) with therapy. In the cats of the second period, gastrointestinal and extranodal lymphomas were the most common anatomical sites, and the majority of those cats were FeLV antigen-negative. Thus, other aetiologies than progressive FeLV infection must have a greater impact on cancerogenesis among affected cats with lymphoma to date.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.