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Possible role for MHC I in bleeding calf syndrome

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RESEARCHERS at the Justus-Liebig university in Germany believe they have discovered why the use of a particular vaccine against bovine viral diarrhoea virus (BVDV) in the adult female cows can lead to their calves developing bovine neonatal pancytopenia (BNP).

Writing in the journal Veterinary Research, the team describes a link between BNP and antibodies against the major histocompatability complex class I (MHC I) proteins. They say that, during their study, they detected alloantibodies reacting with blood leukocytes …

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