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Anthelmintics
Benzimidazole resistance in Nematodirus battus
  1. Siân Mitchell1,
  2. Rebecca Mearns2,
  3. Iain Richards3,
  4. Alison A. Donnan4 and
  5. David J. Bartley4
  1. AHVLA – Carmarthen, Job's Well Road, Johnstown, Carmarthen SA31 3EZ
  2. AHVLA – Penrith, Merrythought, Calthwaite, Penrith, Cumbria CA11 9RR
  3. Westmorland Veterinary Group, Riverside Business Park, Natland Road, Kendal, Cumbria LA9 7SX
  4. Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ
  1. e-mail: sian.mitchell{at}ahvla.gsi.gov.uk

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WE would like to report the results from work investigating a case of suspected benzimidazole resistance in lambs infected with Nematodirus battus. We are aware of benzimidazole resistance having been identified in a New Zealand isolate of Nematodirus spathiger (Middelberg and McKenna 1983), but believe that this is the first confirmed occurrence of such resistance in N battus in any country.

A carcase and faecal material were sent to the Veterinary Laboratories Agency (now the Animal Health and Veterinary Laboratories Agency [AHVLA]) – Penrith by a farmer who was keen to investigate four deaths that had occurred in a batch of 60 two-month-old lambs with diarrhoea in June 2010. Nematodirosis was diagnosed on the basis of postmortem …

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