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Acute phase protein concentrations in dogs with nasal disease
  1. D. Sheahan, BSc, BVSc, CertSAS, MRCVS1,
  3. R. J. Mellanby, BSc, BVMS, PhD, DSAM, DipECVIM-CA, MRCVS3,
  4. A. G. Gow, BVM&S, CertSAM, MRCVS3,
  5. E. Friend, BvetMed, CertSAS, DECVS, MRCVS4,
  6. J. Heller, BSc, BVSc, PhD, MRCVS5,
  7. L. M. Bence, BSc, PhD6 and
  8. P. D. Eckersall, BSc, MBA, PhD, FRCPath2
  1. Division of Companion Animal Sciences, Faculty of Veterinary Medicine, University of Glasgow, Bearsden Road, Glasgow G61 1QH
  2. Division of Animal Production and Public Health, Faculty of Veterinary Medicine, University of Glasgow, Bearsden Road, Glasgow G61 1QH
  3. Division of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Hospital for Small Animals, Roslin, Midlothian EH25 9RG
  4. Small Animal Hospital, University of Bristol Veterinary School, Langford House, Langford, North Somerset BS40 5DU
  5. Boyd Orr Centre for Population and Ecosystem Health, Faculty of Veterinary Medicine, 464 Bearsden Road, University of Glasgow, Glasgow G12 8QQ
  6. ReactivLab, Garscube Estate, Bearsden Road, Glasgow G61 1QH
  1. E-mail for correspondence don.sheahan{at}
  • Dr Heller's present address is School of Animal and Veterinary Science, Charles Stuart University, Locked Bag 588, Wagga Wagga, NSW 2678, Australia

The concentrations of C-reactive protein (CRP), serum amyloid A, haptoglobin (Hp) and α1-acid glycoprotein were measured in dogs with clinical signs of nasal disease and compared with those of healthy dogs in order to determine the expression of these proteins in cases of canine nasal disease. A significant difference (P<0.001) between the symptomatic group and the control group was found for both CRP and Hp. Among the animals with nasal disease, a significant intergroup difference (P<0.05) was found in the expression of Hp between dogs with aspergillosis and those with chronic rhinitis.

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  • Conflict of interest PDE is a director and shareholder of ReactivLab; LB is an employee of ReactivLab.

  • Provenance not commissioned; externally peer reviewed

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