Article Text

PDF
Effects of a modified live CSFV vaccine on the development of PMWS in pigs infected experimentally with PCV-2
  1. Y. Ha, DVM1,
  2. E-M. Lee1,
  3. Y. H. Lee, DVM1,
  4. C. H. Kim, DVM1,
  5. D. Kim, DVM1,
  6. S. Chae, DVM1,
  7. K. K. Ahn, DVM, MS1,
  8. B. Kim, DVM, MS1 and
  9. C. Chae, DVM, MS, PhD,1
  1. 1 Seoul National University, College of Veterinary Medicine, Department of Veterinary Pathology, San 56-1, Shillim-Dong, Gwanak-Gu, Seoul, 151-742, Republic of Korea
  1. Correspondence to Dr C. Chae, e-mail: swine{at}snu.ac.kr

Abstract

The objective of this study was to determine the effect of vaccination against classical swine fever virus (CSFV) on the development of postweaning multisystemic wasting syndrome (PMWS) in conventional pigs infected experimentally with porcine circovirus type 2 (PCV-2). The pigs infected with PCV-2 and immunised with modified live CSFV developed mild to moderate PMWS, whereas none of the pigs infected with PCV-2 alone or immunised with modified live CSFV alone developed PMWS. Lesions histologically characteristic of PMWS were observed in lymph nodes from the pigs infected with PCV-2 and immunised with modified live CSFV vaccine, and extensive replication of PCV-2 was detected in the nodes by in situ hybridisation.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.