Plasma concentrations of voriconazole in falcons
- V. Schmidt, MedVet, DipECAMS1,
- F. Demiraj, DrChem, DipChem2,
- A. Di Somma, MedVet, SMPA3,
- T. Bailey, BSc, BVSc, MSc, PhD, CertZooMed, DipECAMS, MRCVS3,
- F. R. Ungemach, ProfDrMedVet2 and
- M-E. Krautwald-Junghanns, ProfDrMedVet, DipECAMS1
Abstract
Doses of 12·5 mg voriconazole/kg bodyweight administered every 12 hours by crop gavage to six falcons for 14 days provided peak plasma concentrations of more than 1 μg/ml, but the trough concentrations were lower and sometimes undetectable. Administering the same doses incorporated into meat that was fed to one falcon for seven days and to three falcons for up to 91 days provided similar plasma concentrations.
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